Bloodwork Intelligence Analyzer
Instant assessment guide based on anabolic optimal targets and functional medicine safety margins
ALT (GPT)
Primary enzyme leaking into the bloodstream upon hepatocellular injury. Highly sensitive to 17-alpha alkylated oral AAS use.
• Increase NAC to 1,200mg/day + Silymarin (Milk Thistle 500mg)
• Complete abstinence from alcohol and acetaminophen (Tylenol)
• Emergency administration of TUDCA 500–1,000mg/day + NAC 1,800mg
• Immediately halt 17-aa orals and evaluate reducing injectable compound dosages
AST (GOT)
Rises sharply from skeletal muscle damage as well as hepatocytes. Can temporarily spike above 100 post-heavy resistance training.
• Re-test after 48 hours of complete rest from intense training
• Glutathione IV or NAC supplementation
• Concurrent rapid spike with ALT indicates hepatic parenchymal strain → Administer TUDCA 1,000mg
• Run Creatine Kinase (CK) test to rule out rhabdomyolysis
Gamma-GTP (GGT)
Indicator of cholestasis and hepatic detoxification (glutathione depletion). Pure liver-specific marker unaffected by muscle trauma.
• Take NAC 1,200mg to stimulate glutathione synthesis
• Hydration (4L+/day) to prevent biliary stasis
• Risk of cholestatic liver injury → UDCA (Ursofalk) or TUDCA 750mg+ mandatory
• Complete cessation of oral compounds
Total Bilirubin
Reflects red blood cell breakdown metabolism and biliary excretion status. High levels indicate jaundice and cholestasis risk.
• Review hepatoprotective stack if cholestasis is suspected
• Avoid overexertion and fasting
• Potential jaundice onset → Seek immediate medical evaluation and full cycle OFF
Cystatin-C
Gold standard for renal glomerular filtration rate, unaffected by muscle mass or protein intake. Top priority test for bodybuilder kidney assessment.
• Aggressively increase daily water intake to 4–5L
• Strict blood pressure control (target < 120/80 mmHg)
• Active glomerular injury in progress → Immediately drop nephrotoxic compounds (Trenbolone, orals)
• Administer Astragalus extract (3,000mg/day) and consult nephrology
Serum Creatinine
Muscle metabolite. Can elevate up to 1.4–1.6 without renal pathology in high muscle mass or creatine supplement users.
• Temporarily halt creatine supplementation and cross-reference with Cystatin-C
• Maintain hydration during high-protein diets
• Concurrent elevation with Cystatin-C indicates acute kidney injury → Cycle OFF and immediate BP reduction
eGFR (Estimated GFR)
Overall metric of renal filtration capacity. Values below 60 signal chronic kidney function decline.
• Account for creatinine distortion via high muscle mass → Recalculate using Cystatin-C formula
• Persistent values < 60 risk irreversible renal damage → Cease all PEDs and undergo nephrology workup
ApoB (Apolipoprotein B)
Total count of atherogenic particles penetrating arterial walls. Supremely more accurate cardiovascular risk factor than LDL-C.
• Consider Citrus Bergamot 1,000mg/day + Ezetimibe (10mg prescription)
• Restrict saturated fat intake
• Rapid plaque formation risk → Add statin (Rosuvastatin 5–10mg) or immediately drop orals
Hematocrit (HCT)
Red blood cell volume ratio in blood. Excessive erythrocesis from AAS thickens blood, triggering stroke/myocardial infarction risks.
• Daily hydration > 4.5L + Naringin (grapefruit extract) supplementation
• Zone 2 cardio 3-4x/week mandatory
• > 54% spikes thrombosis risk → Immediate therapeutic phlebotomy/blood donation (400–500mL)
• Reduce EPO-stimulating compounds
hs-CRP (High-Sensitivity CRP)
Vascular wall micro-inflammation marker. Reflects endothelial damage and lipid plaque rupture vulnerability.
• High-potency Omega-3 (EPA+DHA 4,000mg/day) + Curcumin supplementation
• Treat periodontal and joint inflammation
• Acute cardiovascular event hazard → Low-dose aspirin (100mg) and vascular workup
HDL Cholesterol
Vascular scavenger role. Frequently crashes below 10 due to hepatic lipase stimulation from oral 17-aa AAS use.
• Niacin (500mg) + high-intensity cardio regimen
• Increase Omega-3 and extra virgin olive oil intake
• Reverse cholesterol transport paralysis → Strictly limit oral cycles to 4-6 weeks max then OFF
Sensitive Estradiol (Sensitive E2)
LC-MS/MS assay mandatory. Critical balance for gynecomastia prevention, water retention, cognitive function, and endothelial protection.
• 40–50 pg/mL: Fine-tune Aromasin (Exemestane) 12.5mg 1-2x/week
• Crash below 20 requires immediate AI cessation
• Spikes > 60 with breast lump/tenderness → Immediately add Nolvadex 20mg to block receptors
Free Testosterone
Unbound fraction acting directly on muscle cell androgen receptors without SHBG restriction.
• Cross-check Free T to Total T ratio to back-calculate SHBG suppression
• Exceeding target requires concurrent monitoring of erythrocytosis (HCT) and blood pressure
SHBG (Sex Hormone-Binding Globulin)
Hormone transport protein. Hepatic synthesis drops below 5 under potent androgens or oral AAS.
• Adjust AI dosing accounting for simultaneous Free E2 and Free T surges from SHBG depletion
• Prolonged suppression < 5 degrades lipid profile and accelerates endocrine fatigue
Prolactin
Spikes via dopamine receptor stimulation during 19-nor use (Trenbolone, Deca-Durabolin). Causes ED/libido loss and galactorrhea.
• Administer Vitamin B6 (Active P5P form 200–300mg/day)
• Normalize E2 to suppress prolactin receptor hypersensitivity
• Nipple discharge/erectile dysfunction onset → Cabergoline (Dostinex) 0.25mg 1–2x/week
